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Higher doses are associated with potential side effects such as severe abdominal pain, stomach problems, nausea, vomiting, diarrhea, and constipation

f , Proportion of SCA showing each group

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CONCLUSION AND PERSPECTIVES During the purine catabolism, there are three major purine bases and their corresponding ribonucleosides, which consist of adenine/adenosine, G/Gr, and Hx/inosine ( Figure 2 )